cyclic gmp — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T36983	Cyclic-di-GMP disodium	Cyclic diguanylate,5GP-5GP disodium,3',5'-Cyclic diguanylic acid,Cyclic di-GMP (sodium salt),cyclic diguanylate disodium,c-di-GMP,c-di-GMP disodium	STING , Endogenous Metabolite
	Cyclic-di-GMP disodium (5GP-5GP disodium) is a bacterial second messenger and a STING agonist involved in a variety of prokaryotic processes including biofilm formation, motility, and cell cycle progression.Cyclic-di-GMP...		STING , Endogenous Metabolite
T10909	Cyclic-di-GMP	c-di-GMP,cyclic diguanylate,5GP-5GP	Others
	Cyclic-di-GMP is a STING agonist and ubiquitous second messenger, which regulates the formation, motility and virulence of biofilms in various bacterial species.		Others
T72243	Cyclic-di-GMP diammonium	5GP-5GP diammonium,c-di-GMP diammonium ; cyclic diguanylate diammonium ; 5GP-5GP diammonium,c-di-GMP diammonium,cyclic diguanylate diammonium
	Cyclic di-GMP (c-di-GMP) diammonium is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species .
T10065L	2',3'-cGAMP sodium	2'-3'-cyclic GMP-AMP sodium	STING , cGAS
	2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium), a cGAMP synthase (cGAS) affecting cytoplasmic DNA production as a second messenger, is a transmembrane bridging protein that is a key component of the cellular innate imm...		STING , cGAS
T5065	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD	Monosodium-GMP,cGMP sodium salt,Cyclic GMP	PKA
	GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, inc...		PKA
T9213	G140		cGAS
	G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS).		cGAS
T12432	PF-06928215		cGAS
	PF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ).		cGAS
T64248	Cyclic-di-GMP sodium
	Cyclic di-GMP sodium (c-di-GMP sodium) is a STING activator and a ubiquitous second messenger that regulates biofilm formation, motility and virulence of various bacteria.
T11673	IRAK4-IN-4		IRAK , cGAS
	IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.		IRAK , cGAS
T5486	RU.521	RU320521	DNA , cGAS
	RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.		DNA , cGAS
T11344	G150		DNA , cGAS
	G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).		DNA , cGAS
T13606	CGAMP	3',3'-cGAMP,Cyclic GMP-AMP	Others
	cGAMP is an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. It also is a STING ligand.		Others
T10065	2',3'-cGAMP	2'-3'-cyclic GMP-AMP	STING , cGAS
	2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a second messenger in cellular innate immunity and is catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. 2',3'-cGAMP binds to STING to form a dimer, inducing the produc...		STING , cGAS
T31597	Ecabapide	DQ2511,DQ 2511,DQ-2511	Others
	Ecabapide (DQ-2511) is a novel gastrointestinal motility promoter that significantly enhances gastric emptying in SHRSP.Ecabapide activates cyclic GMP-dependent housekeeping Cl- channels in rabbit gastric wall cells.		Others
PDK0014	3-Methylxanthine		Endogenous Metabolite
	3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.3-Methylxanthine inhibited xanthine crystallization, it could ...		Endogenous Metabolite
T0167	Vinpocetine	RGH-4405,Ethyl apovincaminate	IκB/IKK , NF-κB , Sodium Channel , PDE
	Vinpocetine (RGH-4405) is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).		IκB/IKK , NF-κB , Sodium Channel , PDE
T31020	CP 461	OSI 461,UNII-68OJX9I7DT,CP-461,CP461	Apoptosis , PDE
	CP 461 (UNII-68OJX9I7DT), a specific PDE2A inhibitor, is a novel pro-apoptotic compound that inhibits cyclic GMP phosphodiesterase but not cyclooxygenase-1 or -2. CP 461 inhibits the growth of a variety of human tumor ce...		Apoptosis , PDE
T3929	Kaurenoic acid	Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid	Others
	Kaurenoic acid (kaurenoate) has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part,...		Others
T16344	NS-2028		Others , Guanylate cyclase
	NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity). It is commonly used in the research of nitric oxide signaling pathways. NS-2028...		Others , Guanylate cyclase
T23009	MMPX		Others
	calmodulin-sensitive cyclic GMP phosphodiesterase inhibitor		Others